From Dr. Mercola:

Mercury is a pernicious neurotoxin. Removing it, however, needs to be done with great care, lest you cause even more problems.

Chris Shade, Ph.D., is probably one of the foremost experts in the world on the subject of heavy metal detoxification, and in this interview, he shares his wisdom on this important topic.

Shade received his Ph.D. from the University of Illinois Urbana-Champaign where he studied the environmental transformations of mercury.

He’s developed a patented liquid chromatographic mercury speciation technology that differentiates and identifies the exactly source of your mercury — whether it’s from your dental amalgams, or from eating contaminated seafood.

He’s also involved in developing new lipid-based delivery systems for nutraceuticals, including liposomes and micro-emulsion systems to address the need for effective and affordable detoxification.

“We had sophisticated computational tools for telling us what kind of ligands (binding molecules) are holding the mercury. What I was tasked with was developing an analytical system for separating different forms of mercury out,” he says.

“You’ve got methylmercury (which is the form that builds up in fish) and then you have inorganic mercury. In the environment, inorganic mercury is everywhere …

I developed these chromatographic tools that would enable a high-throughput analysis of biological samples to separate these different forms.”

The Mercury Tri-Test

In your body, glutathione is the dominant agent that binds to and helps move mercury (and other heavy metals) out of your tissues. Part of effectively eliminating mercury involves methods that help upregulate certain aspects of your chemistry that then mobilizes and moves the mercury out.

I actually used Shade’s diagnostic tests and detox processes about five years ago to help me detox from mercury amalgams, and was able to cut my mercury level down to normal, quite quickly.

The test he developed is called the Mercury Tri-Test, because it looks at three different kinds of samples: blood, hair, and urine. You always have more mercury in your tissues than in your blood. But there’s a steady state or ratio between what’s in your blood and what’s in your tissues.

Hair is an excretion marker for methylmercury, while urine is an excretion marker for inorganic mercury. These levels should be directly proportional to the levels in your blood.

“The most telling of these, the most importantly diagnostic of these ratios, is looking at the inorganic mercury in the blood compared to the inorganic mercury in the urine.

For a given amount of inorganic [mercury] in the blood, there should be roughly a seven-fold increase in the urine, as [mercury] is filtered out in the urine. But what we find that a lot of people have low [mercury in] urine, and high [mercury in their] blood.”

What the Blood to Urine Ratios Indicate

The reason for this has to do with retention toxicity. If two people have 10 amalgams, the sicker of the two will be the one whose urine output of mercury is lower; typically due to damage to

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