From Medical Xpress:

Micrograph showing cortical pseudolaminar necrosis, a finding seen in strokes on medical imaging and at autopsy. H&E-LFB stain. Credit: Nephron/Wikipedia

Researchers from Houston Methodist Hospital and five partner institutions used data from a major stroke clinical study to show that medical centers with more experience and expertise in aggressive medical management had a significantly positive impact on patient outcomes. This, according to research published in the Dec. 15, 2015, issue of Neurology, the medical journal of the American Academy of Neurology.

Conducted from 2008-2013, Stenting and Aggressive Medical Management for the Prevention of Recurrent Ischemic Stroke (SAMMPRIS) was a National Institutes of Health-funded randomized clinical trial conducted at 50 institutions with an enrollment of 451 patients who had suffered strokes or TIAs (also known as ‘mini-strokes’) attributed to severe stenosis (blockage) of a major intracranial artery. The effectiveness of AMM versus stenting as a treatment was compared, with the former resulting in lower rates of recurrence and mortality.

Using the SAMMPRIS patient data, a team led by David Chiu, M.D., medical director of the Houston Methodist Eddy Scurlock Stroke Center and neurologist at the Houston Methodist Neurological Institute, evaluated whether the experience of the stroke center and the expertise of the staff in using AMM for strokes and TIAs led to the better outcomes.

“We compared the rates of recurrent or death for patients receiving aggressive at the 12 centers with the highest study enrollment to those who received the treatment at the 38 with…

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