From Science Daily:
A team of scientists from across the globe have shown that the brains of patients with schizophrenia have the capacity to reorganize and fight the illness. This is the first time that imaging data has been used to show that our brains may have the ability to reverse the effects of schizophrenia.
Schizophrenia is an illness generally associated with a widespread reduction in brain tissue volume. However, a recent study found that a subtle increase in tissue also occurs in certain brain regions.
The study followed 98 patients with schizophrenia and compared them to 83 patients without schizophrenia. The team used Magnetic Resonance Imaging (MRI) and a sophisticated approach called covariance analysis to record the amount of brain tissue increase. Due to the subtlety and the distributed nature of increase, this had not been demonstrated in patients before now.
According to Lawson Health Research Institute’s Dr. Lena Palaniyappan, there is an overarching feeling that curing people with a severe mental illness, such as schizophrenia is not possible. “Even the state-of-art frontline treatments aim merely for a reduction rather than a reversal of the cognitive and functional deficits caused by the illness,” says Dr. Palaniyappan, who is the Medical Director at the Prevention & Early Intervention Program for Psychoses (PEPP) at London Health Sciences Centre (LHSC).
This comes from a long-standing notion that schizophrenia is a degenerative illness, with the seeds of damage sown very early during the course of brain development. “Our results highlight that despite the severity of tissue…